Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors
BackgroundBRCA1- and BRCA2-associated tumors appear to have distinct molecular signatures. BRCA1-associated tumors are predominantly basal-like cancers, whereas BRCA2-associated tumors have a predominant luminal-like phenotype. These two molecular signatures reflect in part the two cell types found...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Springer US
2008
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727582/ |