Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors

BackgroundBRCA1- and BRCA2-associated tumors appear to have distinct molecular signatures. BRCA1-associated tumors are predominantly basal-like cancers, whereas BRCA2-associated tumors have a predominant luminal-like phenotype. These two molecular signatures reflect in part the two cell types found...

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Bibliographic Details
Main Authors: Bane, Anita L., Pinnaduwage, Dushanthi, Colby, Sarah, Bull, Shelley B., O’Malley, Frances P., Andrulis, Irene L.
Format: Online
Language:English
Published: Springer US 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727582/