Structural and biophysical properties of the integrin-associated cytoskeletal protein talin

Talin is a large cytoskeletal protein (2541 amino acid residues) which plays a key role in integrin-mediated events that are crucial for cell adhesion, migration, proliferation and survival. This review summarises recent work on the structure of talin and on some of the structurally better defined i...

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Bibliographic Details
Main Authors: Roberts, Gordon C. K., Critchley, David R.
Format: Online
Language:English
Published: Springer-Verlag 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720171/