Pten Dose Dictates Cancer Progression in the Prostate

Pten Dose Dictates Cancer Progression in the Prostate

Complete inactivation of the PTEN tumor suppressor gene is extremely common in advanced cancer, including prostate cancer (CaP). However, one PTEN allele is already lost in the vast majority of CaPs at presentation. To determine the consequence of PTEN dose variations on cancer progression, we have...

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Bibliographic Details
Main Authors: Trotman, Lloyd C, Niki, Masaru, Dotan, Zohar A, Koutcher, Jason A, Di Cristofano, Antonio, Xiao, Andrew, Khoo, Alan S, Roy-Burman, Pradip, Greenberg, Norman M, Dyke, Terry Van, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo
Format: Online
Language:English
Published: Public Library of Science 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270016/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270016/

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