Clinical use of recombinant human activated factor VII (rFVIIa) in the prevention and treatment of bleeding episodes in patients with Glanzmann’s thrombasthenia

Glanzmann’s thrombasthenia (GT) is a congenital qualitative platelet disorders due to the deficiency or defect of platelet membrane GPIIb/IIIa (integrin αIIbβ3). The standard treatment for bleeding is platelet transfusion but repeated transfusion may result in the development of anti-platelet antibo...

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Bibliographic Details
Main Author: Poon, Man-Chiu
Format: Online
Language:English
Published: Dove Medical Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291310/