GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex
We have examined the role of ras-related rab proteins in transport from the ER to the Golgi complex in vivo using a vaccinia recombinant T7 RNA polymerase virus to express site-directed rab mutants. These mutations are within highly conserved domains involved in guanine nucleotide binding and hydrol...
Format: | Online |
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Language: | English |
Published: |
The Rockefeller University Press
1992
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289685/ |