The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits
The lymphocyte glycoprotein CD4 is constitutively internalized and recycled in nonlymphoid cells, but is excluded from the endocytic pathway in lymphocytic cells (Pelchen-Matthews, A., J. E. Armes, G. Griffiths, and M. Marsh. 1991. J. Exp. Med. 173: 575-587). Inhibition of CD4 endocytosis is depende...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1992
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289416/ |