Specific targeting and toxicity of sulphonated aluminium phthalocyanine photosensitised liposomes directed to cells by monoclonal antibody in vitro.

A partially purified fraction of the water soluble photosensitive dye sulphonated aluminium phthalocyanine (AlSPc) was encapsulated in liposomes which were then linked to a targeting monoclonal antibody 791T/36 using a heterobifunctional linking agent. The photocytotoxic effects of the liposomes wer...

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Bibliographic Details
Main Authors: Morgan, J., Gray, A. G., Huehns, E. R.
Format: Online
Language:English
Published: Nature Publishing Group 1989
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247071/