The Gammaherpesvirus m2 Protein Manipulates the Fyn/Vav Pathway through a Multidocking Mechanism of Assembly
To establish latent infections in B-cells, gammaherpesviruses express proteins in the infected B-cells of the host that spuriously activate signalling pathways located downstream of the B-cell receptor. One such protein is M2, a murine gammaherpesvirus 68-encoded molecule that activates the Vav1/Rac...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Public Library of Science
2008
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244710/ |