A Cross-Talk between TrkB and Ret Tyrosine Kinases Receptors Mediates Neuroblastoma Cells Differentiation
Understanding the interplay between intracellular signals initiated by multiple receptor tyrosine kinases (RTKs) to give the final cell phenotype is a major pharmacological challenge. Retinoic acid (RA)-treatment of neuroblastoma (NB) cells implicates activation of Ret and TrkB RTKs as critical step...
Main Authors: | Esposito, Carla Lucia, D'Alessio, Amelia, de Franciscis, Vittorio, Cerchia, Laura |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2008
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242850/ |
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