Modeling Cancer Progression via Pathway Dependencies
Cancer is a heterogeneous disease often requiring a complexity of alterations to drive a normal cell to a malignancy and ultimately to a metastatic state. Certain genetic perturbations have been implicated for initiation and progression. However, to a great extent, underlying mechanisms often remain...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Public Library of Science
2008
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242820/ |