Unintentional miRNA Ablation Is a Risk Factor in Gene Knockout Studies: A Short Report

One of the most powerful techniques for studying the function of a gene is to disrupt the expression of that gene using genetic engineering strategies such as targeted recombination or viral integration of gene trap cassettes. The tremendous utility of these tools was recognized this year with the a...

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Bibliographic Details
Main Authors: Osokine, Ivan, Hsu, Ruby, Loeb, Gabriel B, McManus, Michael T
Format: Online
Language:English
Published: Public Library of Science 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242815/