Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia

Resiniferatoxin (RTX) is an ultrapotent capsaicin analog that binds to the transient receptor potential channel, vanilloid subfamily member 1 (TRPV1). There is a large body of evidence supporting a role for TRPV1 in noxious-mediated and inflammatory hyperalgesic responses. In this study, we evaluate...

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Bibliographic Details
Main Authors: Neubert, John K, Mannes, Andrew J, Karai, Laszlo J, Jenkins, Alan C, Zawatski, Lanel, Abu-Asab, Mones, Iadarola, Michael J
Format: Online
Language:English
Published: BioMed Central 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242785/