Quantitative telomeric overhang determination using a double-strand specific nuclease

Telomeres terminate in 3′ overhangs that function in end protection and the formation of t-loops. Determining the steps and factors involved in overhang processing is compromised by the inability to easily and accurately determine overhang size in the presence of many kilobases of double-stranded te...

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Bibliographic Details
Main Authors: Zhao, Yong, Hoshiyama, Hirotoshi, Shay, Jerry W., Wright, Woodring E.
Format: Online
Language:English
Published: Oxford University Press 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241892/