Quantitative telomeric overhang determination using a double-strand specific nuclease
Telomeres terminate in 3′ overhangs that function in end protection and the formation of t-loops. Determining the steps and factors involved in overhang processing is compromised by the inability to easily and accurately determine overhang size in the presence of many kilobases of double-stranded te...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2008
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241892/ |