Calcium Regulation of Single Ryanodine Receptor Channel Gating Analyzed Using HMM/MCMC Statistical Methods

Type-II ryanodine receptor channels (RYRs) play a fundamental role in intracellular Ca2+ dynamics in heart. The processes of activation, inactivation, and regulation of these channels have been the subject of intensive research and the focus of recent debates. Typically, approaches to understand the...

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Bibliographic Details
Main Authors: Rosales, Rafael A., Fill, Michael, Escobar, Ariel L.
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234502/