Development of all CD4 T lineages requires nuclear factor TOX
CD8+ cytotoxic and CD4+ helper/inducer T cells develop from common thymocyte precursors that express both CD4 and CD8 molecules. Upon T cell receptor signaling, these cells initiate a differentiation program that includes complex changes in CD4 and CD8 expression, allowing identification of transiti...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
2008
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234360/ |