Mutations in Hydin impair ciliary motility in mice

Chlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility, and mice with Hydin defects develop lethal hydrocephalus. To determine if defects in Hydin cause hydrocephalus through a mechanism involving cilia, we compared the morphology, ultrastructure, and activity of...

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Bibliographic Details
Main Authors: Lechtreck, Karl-Ferdinand, Delmotte, Philippe, Robinson, Michael L., Sanderson, Michael J., Witman, George B.
Format: Online
Language:English
Published: The Rockefeller University Press 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234243/