Effects of Dantrolene on Steps of Excitation-Contraction Coupling in Mammalian Skeletal Muscle Fibers

The effects of the muscle relaxant dantrolene on steps of excitation-contraction coupling were studied on fast twitch muscles of rodents. To identify the site of action of the drug, single fibers for voltage-clamp measurements, heavy SR vesicles for calcium efflux studies and solubilized SR calcium...

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Bibliographic Details
Main Authors: Szentesi, Péter, Collet, Claude, Sárközi, Sándor, Szegedi, Csaba, Jona, István, Jacquemond, Vincent, Kovács, László, Csernoch, László
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233700/