Affinity and Location of an Internal K+ Ion Binding Site in Shaker K Channels

We have examined the interaction between TEA and K+ ions in the pore of Shaker potassium channels. We found that the ability of external TEA to antagonize block of Shaker channels by internal TEA depended on internal K+ ions. In contrast, this antagonism was independent of external K+ concentrations...

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Bibliographic Details
Main Authors: Thompson, Jill, Begenisich, Ted
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233657/