Mechanism of Cgmp-Gated Channel Block by Intracellular Polyamines

Polyamines block the retinal cyclic nucleotide-gated channel from both the intracellular and extracellular sides. The voltage-dependent mechanism by which intracellular polyamines inhibit the channel current is complex: as membrane voltage is increased in the presence of polyamines, current inhibiti...

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Bibliographic Details
Main Authors: Guo, Donglin, Lu, Zhe
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2232895/