Isolation of a Single Carboxyl-Carboxylate Proton Binding Site in the Pore of a Cyclic Nucleotide–Gated Channel
The pore of the catfish olfactory cyclic nucleotide–gated (CNG) channel contains four conserved glutamate residues, one from each subunit, that form a high-affinity binding site for extracellular divalent cations. Previous work showed that these residues form two independent and equivalent high-pKa...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1999
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229637/ |