Hydrogen ion block of the sodium pore in squid giant axons

The block of squid axon sodium channels by H ions was studied using voltage-clamp and internal perfusion techniques. An increase in the concentration of internal permeant ions decreased the block produced by external H ions. The voltage dependence of the block was found to be nonmonotonic: it was re...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1983
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228713/