Towards reconciling structure and function in the nuclear pore complex

The spatial separation between the cytoplasm and the cell nucleus necessitates the continuous exchange of macromolecular cargo across the double-membraned nuclear envelope. Being the only passageway in and out of the nucleus, the nuclear pore complex (NPC) has the principal function of regulating th...

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Bibliographic Details
Main Authors: Lim, Roderick Y. H., Aebi, Ueli, Fahrenkrog, Birthe
Format: Online
Language:English
Published: Springer-Verlag 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228380/