Thrombin has a bimodal effect on glioma cell growth.
Using rat glioma C6 cells as a model, we have found a bimodal effect of alpha-thrombin on cell growth. In C6 cells treated with alpha-thrombin at concentrations from 0.02 nM to 1.0 nM, inhibition of cell proliferation was noted. Because the thrombin receptor agonist peptide TRAP-6 also induced inhib...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
1997
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228214/ |