A phase I/II study of a hypoxic cell radiosensitizer KU-2285 in combination with intraoperative radiotherapy.

A fluorinated 2-nitroimidazole radiosensitizer KU-2285 was given before intraoperative radiotherapy (IORT) to 30 patients with unresectable, unresected or macroscopic residual tumours. Twenty-three patients had pancreatic cancer and five had osteosarcoma. The IORT dose was 30 Gy for unresectable pan...

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Bibliographic Details
Main Authors: Shibamoto, Y., Ohshio, G., Hosotani, R., Nishimura, Y., Manabe, T., Imamura, M., Abe, M.
Format: Online
Language:English
Published: Nature Publishing Group 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228186/