High VEGF with Rapid Growth and Early Metastasis in a Mouse Osteosarcoma Model

A murine model of osteosarcoma was developed to investigate the association between the expression of VEGF and the progression of osteosarcoma. Two human osteosarcoma cell lines with distinct VEGF expressions were introduced into proximal tibiae of immuno-deficient SCID mice, either by direct inject...

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Bibliographic Details
Main Authors: Yang, Shang-You, Yu, Haiying, krygier, Jeffrey E., Wooley, Paul H., Mott, Michael P.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225469/