Loss of p21WAF1/CIP1 expression correlates with disease progression in gastric carcinoma.

Previous studies have shown that tumour-suppressor genes play an important role in the progression of solid tumours. Recently, the p21WAF1/CIP1 tumour-suppressor protein has been reported to work as a critical downstream effector of p53 and a potent inhibitor of cyclin-dependent kinases. Thus, the p...

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Bibliographic Details
Main Authors: Ogawa, M., Maeda, K., Onoda, N., Chung, Y. S., Sowa, M.
Format: Online
Language:English
Published: Nature Publishing Group 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223544/