ATP Dependence of the ICl, swell Channel Varies with Rate of Cell Swelling : Evidence for Two Modes of Channel Activation

Swelling-induced activation of the outwardly rectifying anion current, ICl, swell, is modulated by intracellular ATP. The mechanisms by which ATP controls channel activation, however, are unknown. Whole cell patch clamp was employed to begin addressing this issue. Endogenous ATP production was inhib...

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Bibliographic Details
Main Authors: Bond, Tamara, Basavappa, Srisaila, Christensen, Michael, Strange, Kevin
Format: Online
Language:English
Published: The Rockefeller University Press 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222898/