Stimulatory Effects of Peroxisome Proliferator-Activated Receptor-γ on Fcγ Receptor-Mediated Phagocytosis by Alveolar Macrophages

Stimulatory Effects of Peroxisome Proliferator-Activated Receptor-γ on Fcγ Receptor-Mediated Phagocytosis by Alveolar Macrophages

Alveolar macrophages abundantly express PPAR-γ, with both natural and synthetic agonists maintaining the cell in a quiescent state hyporesponsive to antigen stimulation. Conversely, agonists upregulate expression and function of the cell-surface receptor CD36, which mediates phagocytosis of lipids,...

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Bibliographic Details
Main Authors: Aronoff, David M., Serezani, Carlos H., Carstens, Jennifer K., Marshall, Teresa, Gangireddy, Srinivasa R., Peters-Golden, Marc, Reddy, Raju C.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2220046/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2220046/

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