Acute ENaC Stimulation by cAMP in a Kidney Cell Line is Mediated by Exocytic Insertion from a Recycling Channel Pool

Acute hormonal regulation of the epithelial sodium channel (ENaC) in tight epithelia increases transcellular Na+ transport via trafficking of intracellular channels to the apical surface. The fate of the channels removed from the apical surface following agonist washout is less clear. By repetitivel...

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Bibliographic Details
Main Authors: Butterworth, Michael B., Edinger, Robert S., Johnson, John P., Frizzell, Raymond A.
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217480/