Gating Dynamics of the Acetylcholine Receptor Extracellular Domain
We used single-channel recording and model-based kinetic analyses to quantify the effects of mutations in the extracellular domain (ECD) of the α-subunit of mouse muscle–type acetylcholine receptors (AChRs). The crystal structure of an acetylcholine binding protein (AChBP) suggests that the ECD is c...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2004
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217457/ |