Proton block of rat brain sodium channels. Evidence for two proton binding sites and multiple occupancy

The acid titration function of bilayer-incorporated batrachotoxin (BTX)- modified sodium channels was examined in experiments in which the pH was decreased symmetrically, on both sides of the membrane, or asymmetrically, on only one side. In an attempt to minimize interpretational ambiguities, the e...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1993
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2216752/