Cytoplasmic [Ca2+] and intracellular pH in lymphocytes. Role of membrane potential and volume-activated Na+/H+ exchange

The effect of elevating cytoplasmic Ca2+ [( Ca2+]i) on the intracellular pH (pHi) of thymic lymphocytes was investigated. In Na+- containing media, treatment of the cells with ionomycin, a divalent cation ionophore, induced a moderate cytoplasmic alkalinization. In the presence of amiloride or in Na...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1987
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215895/