Mechanism of osmotic activation of Na+/H+ exchange in rat thymic lymphocytes

The activity of the Na+/H+ exchange system of rat thymic lymphocytes was determined by means of intracellular (pHi) and extracellular pH (pH0) measurements. In isotonic media, the antiport is virtually quiescent at physiological pHi (7.0-7.1), but is greatly activated by cytoplasmic acidification. A...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1985
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215819/