Excitation-contraction coupling in cardiac Purkinje fibers. Effects of caffeine on the intracellular [Ca2+] transient, membrane currents, and contraction

The effects of caffeine on tension, membrane potential, membrane currents, and intracellular [Ca2+], measured as the light emitted by the Ca2+-activated photoprotein aequorin, were studied in canine cardiac Purkinje fibers. An initial, transient, positive inotropic effect of caffeine was accompanied...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1984
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215642/