T Cell Receptor–Induced Calcineurin Activation Regulates T Helper Type 2 Cell Development by Modifying the Interleukin 4 Receptor Signaling Complex

The activation of downstream signaling pathways of both T cell receptor (TCR) and interleukin 4 receptor (IL-4R) is essential for T helper type 2 (Th2) cell development, which is central to understanding immune responses against helminthic parasites and in allergic and autoimmune diseases. However,...

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Bibliographic Details
Main Authors: Yamashita, Masakatsu, Katsumata, Makoto, Iwashima, Makio, Kimura, Motoko, Shimizu, Chiori, Kamata, Tohru, Shin, Tahiro, Seki, Nobuo, Suzuki, Seiichi, Taniguchi, Masaru, Nakayama, Toshinori
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213529/