Functionally Inert HIV-Specific Cytotoxic T Lymphocytes Do Not Play a Major Role in Chronically Infected Adults and Children

The highly sensitive quantitation of virus-specific CD8+ T cells using major histocompatibility complex–peptide tetramer assays has revealed higher levels of cytotoxic T lymphocytes (CTLs) in acute and chronic virus infections than were recognized previously. However, studies in lymphocytic choriome...

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Bibliographic Details
Main Authors: Goulder, Philip J.R., Tang, Yanhua, Brander, Christian, Betts, Michael R., Altfeld, Marcus, Annamalai, Ken, Trocha, Alicja, He, Suqin, Rosenberg, Eric S., Ogg, Graham, O'Callaghan, Christopher A., Kalams, Spyros A., McKinney, Ross E., Mayer, Kenneth, Koup, Richard A., Pelton, Stephen I., Burchett, Sandra K., McIntosh, Kenneth, Walker, Bruce D.
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213508/