Glycan-regulated Antigen Processing of a Protein in the Endoplasmic Reticulum Can Uncover Cryptic Cytotoxic T Cell Epitopes
We and others have shown that influenza A nucleoprotein (NP) targeted to the secretory pathway cannot be processed to yield several cytotoxic T lymphocyte (CTL) epitopes in cell lines that lack the transporter associated with antigen processing (TAP). However, a large COOH-terminal fragment of NP is...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1998
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213365/ |