Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity

Sulfatide derived from the myelin stimulates a distinct population of CD1d-restricted natural killer T (NKT) cells. Cis-tetracosenoyl sulfatide is one of the immunodominant species in myelin as identified by proliferation, cytokine secretion, and CD1d tetramer staining. The crystal structure of mous...

Full description

Bibliographic Details
Main Authors: Zajonc, Dirk M., Maricic, Igor, Wu, Douglass, Halder, Ramesh, Roy, Keshab, Wong, Chi-Huey, Kumar, Vipin, Wilson, Ian A.
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213337/