Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells

Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells

The regulation of acetylation is central for the epigenetic control of lineage-specific gene expression and determines cell fate decisions. We provide evidence that the inhibition of histone deacetylases (HDACs) blocks the endothelial differentiation of adult progenitor cells. To define the mechanis...

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Bibliographic Details
Main Authors: Rössig, Lothar, Urbich, Carmen, Brühl, Thomas, Dernbach, Elisabeth, Heeschen, Christopher, Chavakis, Emmanouil, Sasaki, Ken-ichiro, Aicher, Diana, Diehl, Florian, Seeger, Florian, Potente, Michael, Aicher, Alexandra, Zanetta, Lucia, Dejana, Elisabetta, Zeiher, Andreas M., Dimmeler, Stefanie
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213253/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213253/

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