IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508
Interleukin (IL)-2 is the predominant cytokine that is produced by naive Th cells in a primary response. It is required for proliferation and differentiation of Th precursor cells into effector cells. Initial high-level IL-2 production is followed by its decline, and the concomitant induction of cyt...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
2005
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213245/ |