IL-18–induced CD83+CCR7+ NK helper cells

In addition to their cytotoxic activities, natural killer (NK) cells can have immunoregulatory functions. We describe a distinct “helper” differentiation pathway of human CD56+CD3− NK cells into CD56+/CD83+/CCR7+/CD25+ cells that display high migratory responsiveness to lymph node (LN)–associated ch...

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Bibliographic Details
Main Authors: Mailliard, Robbie B., Alber, Sean M., Shen, Hongmei, Watkins, Simon C., Kirkwood, John M., Herberman, Ronald B., Kalinski, Pawel
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213172/