DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells

DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells

Osteoclasts are bone-resorbing cells that play a pivotal role in bone remodeling. Osteoclasts form large multinuclear giant cells by fusion of mononuclear osteoclasts. How cell fusion is mediated, however, is unclear. We identify the dendritic cell–specific transmembrane protein (DC-STAMP), a putati...

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Bibliographic Details
Main Authors: Yagi, Mitsuru, Miyamoto, Takeshi, Sawatani, Yumi, Iwamoto, Katsuya, Hosogane, Naobumi, Fujita, Nobuyuki, Morita, Kozo, Ninomiya, Ken, Suzuki, Toru, Miyamoto, Kana, Oike, Yuichi, Takeya, Motohiro, Toyama, Yoshiaki, Suda, Toshio
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213087/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213087/

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