In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination

The prevention and treatment of prevalent infectious diseases and tumors should benefit from improvements in the induction of antigen-specific T cell immunity. To assess the potential of antigen targeting to dendritic cells to improve immunity, we incorporated ovalbumin protein into a monoclonal ant...

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Bibliographic Details
Main Authors: Bonifaz, Laura C., Bonnyay, David P., Charalambous, Anna, Darguste, Dara I., Fujii, Shin-Ichiro, Soares, Helena, Brimnes, Marie K., Moltedo, Bruno, Moran, Thomas M., Steinman, Ralph M.
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212731/