Senescent Impairment in Synergistic Cytokine Pathways That Provide Rapid Cardioprotection in the Rat Heart
Pretreatment of rodent hearts with platelet-derived growth factor (PDGF)–AB decreases myocardial injury after coronary occlusion. However, PDGF-AB cardioprotection is diminished in older animals, suggesting that downstream elements mediating and/or synergizing the actions of PDGF-AB may be limited i...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2004
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212728/ |