T Cell Receptor (TCR) Engagement Leads to Activation-induced Splicing of  Tumor Necrosis Factor (TNF) Nuclear Pre-mRNA

Inducible gene expression is primarily regulated at the level of transcription. Additional steps of “processing” pre-mRNA, involved in the regulation of induced gene expression, have not been previously reported. Here we report a novel mechanism of “activation-induced splicing” of preexisting tumor...

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Bibliographic Details
Main Authors: Yang, Yang, Chang, Ju-Fay, Parnes, Jane R., Garrison Fathman, C.
Format: Online
Language:English
Published: The Rockefeller University Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212449/