The Central Role of CD4+ T Cells in the Antitumor Immune Response

The induction of optimal systemic antitumor immunity involves the priming of both CD4+ and CD8+ T cells specific for tumor-associated antigens. The role of CD4+ T helper cells (Th) in this response has been largely attributed to providing regulatory signals required for the priming of major histocom...

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Bibliographic Details
Main Authors: Hung, Kenneth, Hayashi, Robert, Lafond-Walker, Anne, Lowenstein, Charles, Pardoll, Drew, Levitsky, Hyam
Format: Online
Language:English
Published: The Rockefeller University Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212434/