p53 Activates the CD95 (APO-1/Fas) Gene in Response to DNA Damage by Anticancer Drugs

p53 Activates the CD95 (APO-1/Fas) Gene in Response to DNA Damage by Anticancer Drugs

Chemotherapeutic drugs cause DNA damage and kill cancer cells mainly by apoptosis. p53 mediates apoptosis after DNA damage. To explore the pathway of p53-dependent cell death, we investigated if p53-dependent apoptosis after DNA damage is mediated by the CD95 (APO-1/Fas) receptor/ligand system. We i...

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Bibliographic Details
Main Authors: Müller, Martina, Wilder, Sylvia, Bannasch, Detlev, Israeli, David, Lehlbach, Katrin, Li-Weber, Min, Friedman, Scott L., Galle, Peter R., Stremmel, Wolfgang, Oren, Moshe, Krammer, Peter H.
Format: Online
Language:English
Published: The Rockefeller University Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212386/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212386/

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