Highly Biased CDR3 Usage in Restricted Sets of β Chain Variable Regions During Viral Superantigen 9 Response
Superantigens encoded by the mouse mammary tumor virus can stimulate a large proportion of T cells through interaction with germline-encoded regions of the T cell receptor β chain like the hypervariable region 4 (HV4) loop. However, several lines of evidence suggest that somatically generated determ...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1998
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212092/ |