Flavonoids Influence Monocytic GTPase Activity and Are Protective in Experimental Allergic Encephalitis

In the chronic disabling disease multiple sclerosis (MS), migration of monocytes across the blood-brain barrier is a crucial step in the formation of new lesions in the central nervous system (CNS). Infiltrating monocyte-derived macrophages secrete inflammatory mediators such as oxygen radicals, whi...

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Bibliographic Details
Main Authors: Hendriks, Jerome J.A., Alblas, Jacqueline, van der Pol, Susanne M.A., van Tol, Eric A.F., Dijkstra, Christine D., de Vries, Helga E.
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212002/