Down-regulation of Plasminogen Activator Inhibitor 1 Expression Promotes Myocardial Neovascularization by Bone Marrow Progenitors

Human adult bone marrow–derived endothelial progenitors, or angioblasts, induce neovascularization of infarcted myocardium via mechanisms involving both cell surface urokinase-type plasminogen activator, and interactions between β integrins and tissue vitronectin. Because each of these processes is...

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Bibliographic Details
Main Authors: Xiang, Guosheng, Schuster, Michael D., Seki, Tetsunori, Kocher, Alfred A., Eshghi, Shawdee, Boyle, Andrew, Itescu, Silviu
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211987/